| ID | GENE | NAME | ORGANISM | START | SEQ | SCORE | IUPRED | VSL2 | DISOD | ANCHOR | MORFCHIBI | DISOB | PFAM | PHOBIUS | PSIPRED | NCOILS | SLIM INSTANCE | SLIM SCORE | SLIM POS | HUMSAVAR | ELM | PTM IN SEQ | PTM IN FLANK | PPI SUM | PPI MAX | DETECTION TYPE | ASSOC TYPE | UNIPROT ANNOT | UNIPROT LOC | GO MF | GO CC | GO BP | SPR | /\ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P00441 | SOD1 | Superoxide dismutase [Cu-Zn] | HOMO SAPIENS | 93 | DGVADVSIEDSVI | 0.63 | 0.37 | 0.46 | 0.01 | 0.48 | 0.60 | 0.00 | Domain Sod_Cu | INT | E | - | - | - | - | D, Gly94Ala, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Gly94Cys, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Gly94Asp, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Gly94Arg, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Glu101Gly, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Asp102Gly, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Asp102Asn, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Gly94Val, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Ile105Phe, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Glu101Lys, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Val98Met, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400]; D, Ala96Gly, Amyotrophic lateral sclerosis 1 (ALS1) [MIM:105400] | - | 99; 103 | 89; 106; 108 | 1.475 | 1 | pull down, biochemical | CO, DI | - | - | ion binding;enzyme binding;oxidoreductase activity | protein complex;cytoplasm;extracellular space;cytoplasmic membrane-bounded vesicle;cytosol;peroxisome;mitochondrion;organelle;nucleoplasm;extracellular region;lysosome;plasma membrane;nucleus | immune system process;anatomical structure development;cytoskeleton organization;vesicle-mediated transport;response to stress;neurological system process;transport;cellular nitrogen compound metabolic process;cytoskeleton-dependent intracellular transport;homeostatic process;biosynthetic process;circulatory system process;sulfur compound metabolic process;plasma membrane organization;aging | - | || |
| Q16656 | NRF1 | Nuclear respiratory factor 1 | HOMO SAPIENS | 228 | SCKPIWWPEDIPW | 1.69 | 0.35 | 0.22 | 0.02 | 0.45 | 0.96 | 0.00 | Family Nrf1_DNA-bind | INT | C | 106-121; 123-127 | - | - | - | - | - | - | 0.875 | 0.875 | two hybrid | DI | 5 | Nucleus | nucleic acid binding transcription factor activity;DNA binding | nucleoplasm;nucleus;organelle | biosynthetic process;cellular nitrogen compound metabolic process;generation of precursor metabolites and energy;mitochondrion organization | - | || | |
| P07947 | YES1 | Tyrosine-protein kinase Yes | HOMO SAPIENS | 44 | SSSAKGTAVNFSS | 2.36 | 0.42 | 0.94 | 0.97 | 0.28 | 0.29 | 0.00 | - | INT | C | - | - | - | - | - | 45; 46 | 37; 38; 40 | 0.238 | 0.238 | biochemical | CO | 5 | Cell membrane, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Cytosol | kinase activity;enzyme binding;ion binding | cytoplasm;Golgi apparatus;cytosol;microtubule organizing center;plasma membrane;protein complex;organelle | transport;cell motility;cell differentiation;cellular protein modification process;immune system process;response to stress;circulatory system process;signal transduction | - | || | |
| P15151 | PVR | Poliovirus receptor | HOMO SAPIENS | 118 | EGNYTCLFVTFPQ | 2.19 | 0.18 | 0.14 | 0.00 | 0.40 | 0.65 | 0.00 | Domain V-set | EXT | E | - | - | - | - | - | - | - | 1.5 | 0.875 | affinity chromatography technology, two hybrid | DI, PA | 5 | Cell membrane, Secreted | - | cytoplasm;plasma membrane;extracellular space;organelle | locomotion;cell adhesion;cell junction organization;cellular component assembly | - | || | |
| O95817 | BAG3 | BAG family molecular chaperone regulator 3 | HOMO SAPIENS | 245 | PVYHKIQGDDWEP | 2.48 | 0.78 | 0.72 | 0.98 | 0.81 | 0.80 | 0.00 | - | INT | C | 432-452 | H.PV.H | 0.0186 | PVYHKIQGDDWEP | - | 247 | 240; 242; 264 | 1.475 | 1 | pull down, biochemical | CO, DI | 5 | - | - | cytoplasm;cytosol;plasma membrane | response to stress;anatomical structure development;protein folding;signal transduction | - | || | |
| Q8IY67 | RAVER1 | Ribonucleoprotein PTB-binding 1 | HOMO SAPIENS | 217 | LLHSRCLCVDRLP | 2.50 | 0.13 | 0.17 | 0.01 | 0.15 | 0.36 | 0.00 | - | INT | C | - | - | - | - | - | - | - | 0.238 | 0.238 | biochemical | CO | 4 | Nucleus, Cytoplasm | RNA binding | cytoplasm;nucleus | cellular nitrogen compound metabolic process;mRNA processing | - | || | |
| Q9Y6G9 | DYNC1LI1 | Cytoplasmic dynein 1 light intermediate chain 1 | HOMO SAPIENS | 296 | VYKYIVQKLYGFP | 1.00 | 0.03 | 0.08 | 0.02 | 0.14 | 0.70 | 0.00 | Family DLIC | INT | H | - | - | - | - | - | - | - | 0.476 | 0.238 | biochemical | CO | 5 | Cytoplasm, Chromosome, Centromere, Kinetochore, Cytoskeleton, Spindle pole | RNA binding;ion binding | cytoplasm;protein complex;microtubule organizing center;nucleoplasm;plasma membrane;organelle | symbiosis, encompassing mutualism through parasitism;mitotic nuclear division;transport;cell division | - | || | |
| Q14204 | DYNC1H1 | Cytoplasmic dynein 1 heavy chain 1 | HOMO SAPIENS | 3691 | DLCSRVTFVNFTV | 2.34 | 0.20 | 0.42 | 0.29 | 0.23 | 0.28 | 0.00 | Domain AAA_9 | INT | C | 552-572; 1192-1219; 3258-3293; 3295-3307; 3458-3476; 3478-3537; 3539-3557; 3832-3842; 3844-3853 | - | - | - | - | - | 3706 | 0.476 | 0.238 | experimental knowledge based, biochemical | CO | 5 | Cytoplasm, Cytoskeleton | RNA binding;ATPase activity;ion binding | protein complex;cytosol;organelle;microtubule organizing center | cellular component assembly;cytoskeleton organization;transport;immune system process;ribonucleoprotein complex assembly;cell cycle | - | || | |
| O43237 | DYNC1LI2 | Cytoplasmic dynein 1 light intermediate chain 2 | HOMO SAPIENS | 283 | LYKYIVHKTYGFH | 1.62 | 0.07 | 0.12 | 0.02 | 0.13 | 0.48 | 0.00 | Family DLIC | INT | H | - | - | - | - | - | 284; 291; 292 | 297 | 0.476 | 0.238 | biochemical | CO | 5 | Cytoplasm, Cytoskeleton | ion binding | protein complex;cytosol;organelle;microtubule organizing center | immune system process;transport;cytoskeleton organization | - | || | |
| Q14204 | DYNC1H1 | Cytoplasmic dynein 1 heavy chain 1 | HOMO SAPIENS | 3691 | DLCSRVTFVNFTV | 2.34 | 0.20 | 0.42 | 0.29 | 0.23 | 0.28 | 0.00 | Domain AAA_9 | INT | C | 552-572; 1192-1219; 3258-3293; 3295-3307; 3458-3476; 3478-3537; 3539-3557; 3832-3842; 3844-3853 | - | - | - | - | - | 3706 | 0.476 | 0.238 | experimental knowledge based, biochemical | CO | 5 | Cytoplasm, Cytoskeleton | RNA binding;ATPase activity;ion binding | protein complex;cytosol;organelle;microtubule organizing center | cellular component assembly;cytoskeleton organization;transport;immune system process;ribonucleoprotein complex assembly;cell cycle | - | || | |
| Q13618 | CUL3 | Cullin-3 | HOMO SAPIENS | 112 | HQTAMVMIRDILM | 2.19 | 0.07 | 0.13 | 0.01 | 0.07 | 0.62 | 0.00 | Family Cullin | INT | H | - | - | - | - | - | - | - | 0.312 | 0.312 | affinity chromatography technology | PA | 5 | Nucleus, Golgi apparatus | enzyme binding | protein complex;nucleoplasm;cytosol;organelle | transport;cytoskeleton organization;vesicle-mediated transport;cell motility;protein complex assembly;cellular protein modification process;immune system process;response to stress;cellular component assembly;signal transduction;cell death;catabolic process;cell division;cell morphogenesis | - | || | |
| P10599 | TXN | Thioredoxin | HOMO SAPIENS | 22 | LVVVDFSATWCGP | 1.91 | 0.05 | 0.09 | 0.00 | 0.10 | 0.77 | 0.00 | Domain Thioredoxin | INT | E | - | - | - | - | - | - | 44 | 0.438 | 0.438 | two hybrid | DI, PA | - | - | RNA binding;oxidoreductase activity | cytoplasm;nucleus;mitochondrion;organelle;nucleoplasm;cytosol | immune system process;protein folding;cell proliferation;response to stress;homeostatic process;biosynthetic process;sulfur compound metabolic process;signal transduction;cell-cell signaling;cellular nitrogen compound metabolic process;small molecule metabolic process | - | || | |
| Q9BTE6 | AARSD1 | Alanyl-tRNA editing protein Aarsd1 | HOMO SAPIENS | 196 | IRVVNIEGVDSNM | 1.30 | 0.35 | 0.29 | 0.01 | 0.34 | 0.58 | 0.00 | Domain tRNA_SAD | INT | C | - | - | - | - | - | 198; 204 | - | 0.562 | 0.312 | affinity chromatography technology, anti tag coimmunoprecipitation | A, PA | 3 | Cytoplasm | ligase activity;RNA binding;ion binding | cytoplasm;nucleus | tRNA metabolic process;cellular amino acid metabolic process | - | || | |
| O60216 | RAD21 | Double-strand-break repair protein rad21 homolog | HOMO SAPIENS | 489 | MPPQQVEQMEIPP | 2.51 | 0.93 | 0.99 | 0.87 | 0.86 | 0.67 | 0.00 | - | INT | C | 530-548; 550-553 | P.P..P | 0.0022 | MPPQQVEQMEIPP | - | - | - | 0.438 | 0.438 | two hybrid | DI, PA | 5 | Nucleus, Chromosome, Centromere | nucleic acid binding transcription factor activity | protein complex;nucleoplasm;cytosol;chromosome | response to stress;cellular protein modification process;biosynthetic process;cellular nitrogen compound metabolic process;cell division;DNA metabolic process;chromosome segregation;mitotic nuclear division;cell death;cell cycle | - | || | |
| O95425 | SVIL | Supervillin | HOMO SAPIENS | 1018 | FSMAKMNAQGNLD | 1.83 | 0.63 | 0.70 | 0.97 | 0.69 | 0.48 | 0.00 | - | INT | C | 99-119 | - | - | - | - | - | - | 1 | 1 | pull down | DI | 5 | Cell membrane, Cytoplasm, Cytoskeleton, Cell projection, Invadopodium, Podosome, Midbody, Cleavage furrow | cytoskeletal protein binding | cytoplasm;protein complex;nucleus;cytoskeleton;plasma membrane;organelle | anatomical structure development;cytoskeleton organization | - | || | |
| P55854 | SUMO3 | Small ubiquitin-related modifier 3 | HOMO SAPIENS | 82 | TIDVFQQQTGGVP | 0.54 | 0.64 | 0.66 | 0.03 | 0.43 | 0.73 | 0.00 | Family Rad60-SLD | INT | E | - | - | - | - | - | - | - | 0.238 | 0.238 | biochemical | CO | - | - | - | cytoplasm;nucleoplasm;nucleus;protein complex;organelle | DNA metabolic process;response to stress;cellular protein modification process | - | || | |
| P05067 | APP | Amyloid beta A4 protein | HOMO SAPIENS | 174 | CGIDKFRGVEFVC | 1.62 | 0.15 | 0.15 | 0.11 | 0.59 | 0.50 | 0.00 | Domain APP_Cu_bd | EXT | C | 231-243; 245-252; 405-425; 432-466; 564-584 | - | - | - | - | - | - | 0.5 | 0.5 | pull down | DI | 5 | Membrane, Clathrin-coated pit | enzyme regulator activity;DNA binding;enzyme binding;ion binding | cytoplasm;Golgi apparatus;extracellular space;cytosol;extracellular region;plasma membrane;protein complex;endosome;organelle | immune system process;anatomical structure development;vesicle-mediated transport;neurological system process;transport;response to stress;cellular protein modification process;cytoskeleton-dependent intracellular transport;homeostatic process;membrane organization;cellular nitrogen compound metabolic process;extracellular matrix organization;signal transduction;cell adhesion;growth;cell death;developmental maturation;mRNA processing | - | || | |
| Q03252 | LMNB2 | Lamin-B2 | HOMO SAPIENS | 492 | EIAYKFTPKYILR | 1.12 | 0.26 | 0.17 | 0.03 | 0.46 | 0.63 | 0.00 | Domain LTD | INT | E | 23-60; 62-65; 74-121; 123-123; 145-182; 184-201; 240-243; 245-261; 284-304; 306-362 | - | - | - | - | 495 | - | 0.238 | 0.238 | biochemical | CO | 5 | Nucleus inner membrane | structural molecule activity | protein complex | - | - | || | |
| P55786 | NPEPPS | Puromycin-sensitive aminopeptidase | HOMO SAPIENS | 213 | LSNMNVIDRKPYP | 1.87 | 0.32 | 0.39 | 0.03 | 0.06 | 0.66 | 0.00 | Family Peptidase_M1 | INT | C | - | - | - | - | - | 214 | - | 0.238 | 0.238 | biochemical | CO | 5 | Cytoplasm, Cytosol, Nucleus | peptidase activity;ion binding | nucleus;cytosol;organelle | immune system process;response to stress;catabolic process;cellular nitrogen compound metabolic process;cellular protein modification process | - | || | |
| P63172 | DYNLT1 | Dynein light chain Tctex-type 1 | HOMO SAPIENS | 34 | YQHSKVNQWTTNV | 1.78 | 0.29 | 0.36 | 0.01 | 0.06 | 0.70 | 0.00 | Family Tctex-1 | INT | H | - | - | - | - | - | - | - | 0.638 | 0.5 | two hybrid, experimental interaction detection | A, PA | - | - | - | protein complex;Golgi apparatus;organelle | locomotion;cytoskeleton organization;transport;symbiosis, encompassing mutualism through parasitism;mitotic nuclear division;cell division | - | || | |
| P06241 | FYN | Tyrosine-protein kinase Fyn | HOMO SAPIENS | 376 | AGMAYIERMNYIH | 2.09 | 0.08 | 0.19 | 0.01 | 0.05 | 0.62 | 0.00 | Domain Pkinase_Tyr | INT | H | - | - | - | - | - | - | - | - | - | - | - | - | - | ion binding;kinase activity;cytoskeletal protein binding | protein complex;nucleus;mitochondrion;plasma membrane;endosome;cytosol | cell proliferation;transport;cell motility;neurological system process;cell differentiation;cellular protein modification process;immune system process;response to stress;signal transduction;cell adhesion;symbiosis, encompassing mutualism through parasitism;anatomical structure development | - | || | |
| P20273 | CD22 | B-cell receptor CD22 | HOMO SAPIENS | 467 | LGVLKIQNVGWDN | 3.47 | 0.26 | 0.15 | 0.03 | 0.22 | 0.44 | 0.00 | Domain Ig_2 | EXT | C | - | - | - | - | - | - | - | - | - | - | - | 5 | Cell membrane | - | organelle | cell adhesion | - | || | |
| P02545 | LMNA | Prelamin-A/C | HOMO SAPIENS | 176 | LGEAKKQLQDEML | 1.79 | 0.48 | 0.80 | 0.04 | 0.23 | 0.37 | 0.00 | Family Filament | INT | H | 28-60; 62-70; 79-121; 123-182; 184-224; 246-273; 296-304; 306-365; 367-375 | L.R | 0.0143 | LGEAKKQLQDEML | - | - | - | 0.238 | 0.238 | biochemical | CO | 5 | Nucleus, Nucleus envelope, Nucleus lamina, Nucleoplasm, Nucleus speckle | structural molecule activity | cytoplasm;protein complex;nucleus;nuclear envelope;nucleoplasm;cytosol | anatomical structure development;cytoskeleton organization;transport;nucleocytoplasmic transport;membrane organization;response to stress;signal transduction;cell death;cell cycle | - | || | |
| P51617 | IRAK1 | Interleukin-1 receptor-associated kinase 1 | HOMO SAPIENS | 296 | LEDRLHCQTQACP | 1.54 | 0.25 | 0.32 | 0.03 | 0.04 | 0.33 | 0.00 | Domain Pkinase | INT | C | - | - | - | - | - | - | - | - | - | - | - | 5 | Cytoplasm, Nucleus, Lipid droplet | kinase activity;signal transducer activity;ion binding | protein complex;cytoplasm;nucleus;lipid particle;plasma membrane;cytosol | aging;protein complex assembly;cellular protein modification process;immune system process;response to stress;signal transduction | - | || | |
| O00203 | AP3B1 | AP-3 complex subunit beta-1 | HOMO SAPIENS | 248 | LTRYARTQFVSPW | 2.04 | 0.19 | 0.20 | 0.06 | 0.18 | 0.50 | 0.00 | Family Adaptin_N | INT | H | 41-60; 62-62 | - | - | - | - | - | - | - | - | - | - | 5 | Cytoplasmic vesicle, Clathrin-coated vesicle membrane, Golgi apparatus | enzyme binding | protein complex;Golgi apparatus | vesicle-mediated transport;vacuolar transport;transport;protein targeting;immune system process;cytoskeleton-dependent intracellular transport | - | || | |
| Q13936 | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha-1C | HOMO SAPIENS | 289 | LFMGKMHKTCYNQ | 2.28 | 0.06 | 0.24 | 0.02 | 0.06 | 0.11 | 0.00 | Family Ion_trans | INT | C | 768-792; 794-795; 1645-1646; 1648-1666 | - | - | - | - | - | - | - | - | - | - | 5 | Membrane, Cell membrane | transmembrane transporter activity;ion binding;enzyme binding;cytoskeletal protein binding | protein complex;cytoplasm;cytosol;plasma membrane | vesicle-mediated transport;neurological system process;transport;homeostatic process;small molecule metabolic process;cell-cell signaling;generation of precursor metabolites and energy;transmembrane transport;signal transduction | - | || | |
| P14672 | SLC2A4 | Solute carrier family 2, facilitated glucose transporter member 4 | HOMO SAPIENS | 355 | LGLAGMCGCAILM | 1.69 | 0.01 | 0.06 | 0.04 | 0.05 | 0.45 | 0.00 | Family Sugar_tr | INT | H | 254-281 | - | - | - | P, Ala358Val, - | - | - | 368 | - | - | - | - | - | - | transmembrane transporter activity | cytoplasmic membrane-bounded vesicle;cytosol;endosome;organelle;plasma membrane | transport;carbohydrate metabolic process;cell differentiation;response to stress;homeostatic process;membrane organization;biosynthetic process;small molecule metabolic process;transmembrane transport | - | || |
| Q9BQS6 | HSPB9 | Heat shock protein beta-9 | HOMO SAPIENS | 77 | LMVTGQQQLDVRD | 1.61 | 0.47 | 0.45 | 0.03 | 0.29 | 0.55 | 0.00 | Family HSP20 | INT | E | - | - | - | - | - | - | - | 1.125 | 0.625 | anti bait coimmunoprecipitation, two hybrid | PA | 3 | Cytoplasm, Nucleus | - | cytoplasm;nucleus | - | - | || | |
| Q9BQS6 | HSPB9 | Heat shock protein beta-9 | HOMO SAPIENS | 77 | LMVTGQQQLDVRD | 1.61 | 0.47 | 0.45 | 0.03 | 0.29 | 0.55 | 0.00 | Family HSP20 | INT | E | - | - | - | - | - | - | - | 1.125 | 0.625 | anti bait coimmunoprecipitation, two hybrid | PA | 3 | Cytoplasm, Nucleus | - | cytoplasm;nucleus | - | - | || | |
| P47712 | PLA2G4A | Cytosolic phospholipase A2 | HOMO SAPIENS | 354 | IGMAKYGTFMAPD | 2.00 | 0.11 | 0.21 | 0.01 | 0.06 | 0.44 | 0.00 | Family PLA2_B | INT | C | - | - | - | - | - | 359 | 370 | - | - | - | - | 5 | Cytoplasm, Cytoplasmic vesicle | lipid binding;ion binding | cytoplasm;cytoplasmic membrane-bounded vesicle;cytosol;Golgi apparatus | transport;lipid metabolic process;cellular amino acid metabolic process;cellular nitrogen compound metabolic process;biosynthetic process;small molecule metabolic process;catabolic process | - | || | |
| P16885 | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | HOMO SAPIENS | 511 | QTMEEEVPQDIPP | 1.64 | 0.59 | 0.61 | 0.04 | 0.07 | 0.71 | 0.00 | - | INT | C | 1212-1219; 1221-1233 | - | - | - | - | - | - | - | - | - | - | 5 | - | signal transducer activity | cytosol;organelle;plasma membrane | immune system process;cell differentiation;lipid metabolic process;transport;biosynthetic process;homeostatic process;response to stress;small molecule metabolic process;catabolic process;signal transduction | - | || | |
| Q9Y6G9 | DYNC1LI1 | Cytoplasmic dynein 1 light intermediate chain 1 | HOMO SAPIENS | 296 | VYKYIVQKLYGFP | 1.00 | 0.03 | 0.08 | 0.02 | 0.14 | 0.70 | 0.00 | Family DLIC | INT | H | - | - | - | - | - | - | - | 0.476 | 0.238 | biochemical | CO | 5 | Cytoplasm, Chromosome, Centromere, Kinetochore, Cytoskeleton, Spindle pole | RNA binding;ion binding | cytoplasm;protein complex;microtubule organizing center;nucleoplasm;plasma membrane;organelle | symbiosis, encompassing mutualism through parasitism;mitotic nuclear division;transport;cell division | - | || | |
| O14576 | DYNC1I1 | Cytoplasmic dynein 1 intermediate chain 1 | HOMO SAPIENS | 148 | LGVSKVTQVDFLP | 8.43 | 0.33 | 0.59 | 0.42 | 0.83 | 0.62 | 0.00 | Family Dynein_IC2 | INT | C | 4-41 | P.E.V | 0.0276 | LGVSKVTQVDFLP | - | - | 165 | 0.875 | 0.875 | two hybrid | DI | 5 | Cytoplasm, Chromosome, Centromere, Kinetochore, Cytoskeleton, Spindle pole | cytoskeletal protein binding | cytoplasm;protein complex;cytosol;organelle;endosome;nucleus | immune system process;cytoskeleton-dependent intracellular transport | - | || | |
| Q9NP97 | DYNLRB1 | Dynein light chain roadblock-type 1 | HOMO SAPIENS | 15 | KGVQGIIVVNTEG | 0.92 | 0.34 | 0.28 | 0.01 | 0.29 | 0.84 | 0.00 | Domain Robl_LC7 | INT | C | - | - | - | - | - | - | - | 0.238 | 0.238 | biochemical | CO | 5 | Cytoplasm, Cytoskeleton | - | cytoplasm;protein complex;microtubule organizing center;organelle;cilium | transport | - | || | |
| Q03188 | CENPC | Centromere protein C | HOMO SAPIENS | 856 | LKVYKTLDTPFFS | 2.05 | 0.15 | 0.26 | 0.01 | 0.14 | 0.36 | 0.00 | Domain CENP-C_C | INT | C | - | - | - | - | - | - | - | - | - | - | - | 5 | Nucleus, Chromosome, Centromere, Kinetochore | DNA binding | cytoplasm;protein complex;nucleus;organelle;nucleoplasm;cytosol | cellular component assembly;chromosome organization;protein complex assembly;macromolecular complex assembly;cell division;chromosome segregation;mitotic nuclear division;cell cycle;signal transduction | - | || | |
| Q03431 | PTH1R | Parathyroid hormone/parathyroid hormone-related peptide receptor | HOMO SAPIENS | 417 | FGVHYIVFMATPY | 1.76 | 0.01 | 0.07 | 0.01 | 0.03 | 0.49 | 0.00 | Family 7tm_2 | EXT | H | - | - | - | - | - | - | - | 0.875 | 0.875 | two hybrid | DI | 5 | Cell membrane | signal transducer activity | cytoplasm;protein complex;nucleus;organelle;plasma membrane;cytosol | anatomical structure development;aging;cell differentiation;homeostatic process;signal transduction;developmental maturation | - | || | |
| O95425 | SVIL | Supervillin | HOMO SAPIENS | 1018 | FSMAKMNAQGNLD | 1.83 | 0.63 | 0.70 | 0.97 | 0.69 | 0.48 | 0.00 | - | INT | C | 99-119 | - | - | - | - | - | - | 1 | 1 | pull down | DI | 5 | Cell membrane, Cytoplasm, Cytoskeleton, Cell projection, Invadopodium, Podosome, Midbody, Cleavage furrow | cytoskeletal protein binding | cytoplasm;protein complex;nucleus;cytoskeleton;plasma membrane;organelle | anatomical structure development;cytoskeleton organization | - | || | |
| O95425 | SVIL | Supervillin | HOMO SAPIENS | 1018 | FSMAKMNAQGNLD | 1.83 | 0.63 | 0.70 | 0.97 | 0.69 | 0.48 | 0.00 | - | INT | C | 99-119 | - | - | - | - | - | - | 1 | 1 | pull down | DI | 5 | Cell membrane, Cytoplasm, Cytoskeleton, Cell projection, Invadopodium, Podosome, Midbody, Cleavage furrow | cytoskeletal protein binding | cytoplasm;protein complex;nucleus;cytoskeleton;plasma membrane;organelle | anatomical structure development;cytoskeleton organization | - | || | |
| O14908 | GIPC1 | PDZ domain-containing protein GIPC1 | HOMO SAPIENS | 37 | GGGSGGPQMGLPP | 1.24 | 0.87 | 0.96 | 0.97 | 0.38 | 0.23 | 0.00 | - | INT | C | - | - | - | - | - | - | - | 0 | 0 | experimental knowledge based | - | - | - | cytoskeletal protein binding | cytoplasmic membrane-bounded vesicle;cytoplasm;cytosol;organelle | cell-cell signaling;cell motility;transport;signal transduction;protein targeting | - | || | |
| Q9GZM8 | NDEL1 | Nuclear distribution protein nudE-like 1 | HOMO SAPIENS | 219 | TPVGKGTENTFPS | 1.38 | 0.66 | 0.81 | 0.98 | 0.22 | 0.15 | 0.08 | Family NUDE_C | INT | C | 30-60; 62-101; 105-121; 123-182; 184-190 | - | - | - | - | 219; 231 | 213; 215; 241 | 0 | 0 | experimental knowledge based | - | - | - | peptidase activity;cytoskeletal protein binding | protein complex;cytoskeleton;cytoplasmic membrane-bounded vesicle;cytosol;nuclear envelope;microtubule organizing center;organelle | cytoskeleton organization;growth;cell proliferation;cell motility;cytoskeleton-dependent intracellular transport;membrane organization;signal transduction;chromosome segregation;cell cycle | - | || | |
| P01138 | NGF | Beta-nerve growth factor | HOMO SAPIENS | 142 | WVGDKTTATDIKG | 2.11 | 0.31 | 0.38 | 0.01 | 0.14 | 0.44 | 0.00 | Domain NGF | EXT | E | - | - | - | - | - | - | - | 0 | 0 | experimental knowledge based | - | 5 | Secreted | enzyme regulator activity;signal transducer activity | cytoplasmic membrane-bounded vesicle;extracellular region;endosome | protein maturation;neurological system process;anatomical structure development;cellular nitrogen compound metabolic process;signal transduction;cell-cell signaling;cell death | - | || | |
| P43034 | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha | HOMO SAPIENS | 106 | GHRSPVTRVIFHP | 2.94 | 0.26 | 0.31 | 0.01 | 0.33 | 0.88 | 0.00 | - | INT | C | 58-60; 62-79 | - | - | - | - | 109 | - | 0 | 0 | experimental knowledge based | - | 5 | Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Spindle, Nucleus membrane | cytoskeletal protein binding;enzyme binding;ion binding | protein complex;cytosol;nuclear envelope;microtubule organizing center;cilium;organelle | cellular component assembly;cytoskeleton organization;lipid metabolic process;cell motility;neurological system process;cell proliferation;cell division;cytoskeleton-dependent intracellular transport;membrane organization;cellular nitrogen compound metabolic process;small molecule metabolic process;cell-cell signaling;signal transduction;transport;anatomical structure formation involved in morphogenesis;cell differentiation;mitotic nuclear division;catabolic process;cell cycle;anatomical structure development | - | || | |
| O75449 | KATNA1 | Katanin p60 ATPase-containing subunit A1 | HOMO SAPIENS | 351 | KMVMVLAATNFPW | 2.91 | 0.28 | 0.23 | 0.13 | 0.33 | 0.71 | 0.00 | Family AAA | INT | C | - | - | - | - | - | - | - | 0 | 0 | experimental knowledge based | - | 5 | Cytoplasm, Midbody, Cytoskeleton, Microtubule organizing center, Centrosome, Spindle pole | ion binding;ATPase activity;cytoskeletal protein binding | protein complex;cytoplasm;nucleus;lipid particle;microtubule organizing center;plasma membrane;organelle | mitotic nuclear division;cytoskeleton organization;cell division;cell motility | - | || | |
| P23560 | BDNF | Brain-derived neurotrophic factor | HOMO SAPIENS | 177 | LKQYFYETKCNPM | 1.08 | 0.25 | 0.33 | 0.02 | 0.26 | 0.86 | 0.00 | Domain NGF | EXT | E | - | - | - | - | - | - | 191 | 0 | 0 | experimental knowledge based | - | - | Secreted | - | cytoplasmic membrane-bounded vesicle;cytoplasm;extracellular space | cellular component assembly;growth;neurological system process;anatomical structure development;cell differentiation;response to stress;signal transduction;transport;cell-cell signaling;generation of precursor metabolites and energy | - | || | |
| Q16620 | NTRK2 | BDNF/NT-3 growth factors receptor | HOMO SAPIENS | 112 | LKNSNLQHINFTR | 1.96 | 0.17 | 0.36 | 0.01 | 0.06 | 0.65 | 0.00 | - | EXT | C | - | - | - | - | - | - | - | 0 | 0 | experimental knowledge based | - | 5 | Cell membrane, Endosome membrane | kinase activity;signal transducer activity;ion binding | protein complex | anatomical structure development;cell motility;neurological system process;cell differentiation;cellular protein modification process;signal transduction | - | || | |
| P49795 | RGS19 | Regulator of G-protein signaling 19 | HOMO SAPIENS | 41 | LCWCCCCSCSWNQ | 1.76 | 0.01 | 0.93 | 0.43 | 0.09 | 0.48 | 0.01 | - | INT | C | - | - | - | - | - | - | - | 0 | 0 | experimental knowledge based | - | - | - | enzyme regulator activity | cytoplasm;Golgi apparatus;protein complex;plasma membrane;cytoplasmic membrane-bounded vesicle | autophagy;signal transduction | - | || | |
| Q05193 | DNM1 | Dynamin-1 | HOMO SAPIENS | 138 | PGMTKVPVGDQPP | 3.71 | 0.42 | 0.44 | 0.10 | 0.08 | 0.30 | 0.00 | Family Dynamin_N | INT | C | 301-304; 306-322 | - | - | - | - | - | - | 0 | 0 | experimental knowledge based | - | 5 | Cytoplasm, Cytoskeleton | GTPase activity;RNA binding;enzyme binding;ion binding | protein complex;organelle;plasma membrane | transport;vesicle-mediated transport;neurological system process;protein complex assembly;signal transduction;cell-cell signaling | - | || | |
| Q9Y5Y9 | SCN10A | Sodium channel protein type 10 subunit alpha | HOMO SAPIENS | 711 | EMVFKIIAFDPYY | 2.20 | 0.00 | 0.04 | 0.01 | 0.02 | 0.48 | 0.00 | Family Ion_trans | INT | H | 403-426; 428-438 | - | - | - | - | 723 | 724 | - | - | - | - | 5 | Membrane | transmembrane transporter activity | protein complex;organelle | neurological system process;transport;transmembrane transport | - | || | |
| P04629 | NTRK1 | High affinity nerve growth factor receptor | HOMO SAPIENS | 290 | LHTAVEMHHWCIP | 1.88 | 0.19 | 0.16 | 0.02 | 0.17 | 0.47 | 0.00 | - | EXT | E | - | - | - | - | - | - | - | 0 | 0 | experimental knowledge based | - | 5 | Cell membrane, Early endosome membrane, Late endosome membrane | kinase activity;signal transducer activity;enzyme binding;ion binding | protein complex;endosome;organelle;plasma membrane | anatomical structure development;aging;neurological system process;cell differentiation;cellular protein modification process;immune system process;response to stress;signal transduction;cell death | - | || | |
| P08100 | RHO | Rhodopsin | HOMO SAPIENS | 306 | YIMMNKQFRNCML | 1.91 | 0.02 | 0.11 | 0.16 | 0.06 | 0.55 | 0.00 | Family 7tm_1 | INT | H | - | - | - | - | - | 306 | 301 | - | - | - | - | - | - | signal transducer activity;ion binding | Golgi apparatus;plasma membrane;cilium | neurological system process;anatomical structure development;lipid metabolic process;cellular protein modification process;signal transduction | - | || | |
| O14641 | DVL2 | Segment polarity protein dishevelled homolog DVL-2 | HOMO SAPIENS | 675 | LPYNPMMVVMMPP | 2.72 | 0.84 | 0.99 | 0.99 | 0.84 | 0.71 | 0.00 | Family Dsh_C | INT | C | - | - | - | - | - | - | - | 0.138 | 0.138 | experimental interaction detection | A | 5 | Cell membrane, Cytoplasm, Cytosol, Cytoplasmic vesicle | - | cytoplasm;cytoplasmic membrane-bounded vesicle;nucleus;organelle;plasma membrane;cytosol | biosynthetic process;anatomical structure development;cellular nitrogen compound metabolic process;anatomical structure formation involved in morphogenesis;signal transduction | - | || | |
| O14640 | DVL1 | Segment polarity protein dishevelled homolog DVL-1 | HOMO SAPIENS | 534 | LGQGYPYQYPGPP | 2.57 | 0.55 | 0.93 | 0.89 | 0.61 | 0.85 | 0.00 | Family Dsh_C | INT | C | - | PY | 0.0030 | LGQGYPYQYPGPP | - | - | - | 0.138 | 0.138 | experimental interaction detection | A | 5 | Cell membrane, Cytoplasm, Cytosol, Cytoplasmic vesicle | enzyme binding | protein complex;cytoplasmic membrane-bounded vesicle;cytosol;organelle | anatomical structure development;cytoskeleton organization;growth;transport;cellular nitrogen compound metabolic process;membrane organization;biosynthetic process;signal transduction | - | || | |
| Q07866 | KLC1 | Kinesin light chain 1 | HOMO SAPIENS | 450 | GGWYKACKVDSPT | 3.19 | 0.34 | 0.29 | 0.01 | 0.59 | 0.83 | 0.00 | - | INT | H | 90-121; 123-153 | - | - | - | - | 460; 462; 460 | 445; 449; 464; 465; 449 | - | - | - | - | 5 | Cell projection, Growth cone, Cytoplasmic vesicle, Cytoskeleton | - | cytoplasmic membrane-bounded vesicle;protein complex;cytosol | immune system process;symbiosis, encompassing mutualism through parasitism;signal transduction;cytoskeleton-dependent intracellular transport | - | || | |
| Q9H0B6 | KLC2 | Kinesin light chain 2 | HOMO SAPIENS | 435 | GSWYKACKVDSPT | 2.81 | 0.39 | 0.38 | 0.01 | 0.68 | 0.75 | 0.00 | - | INT | H | 86-121; 123-142 | - | - | - | - | 436; 438; 445 | 428; 431; 434 | - | - | - | - | 5 | Cytoplasm, Cytoskeleton | cytoskeletal protein binding | protein complex;cytosol | immune system process;signal transduction;cytoskeleton-dependent intracellular transport | - | || |